Uso de algunos anthistamínicos, antimuscarinicos y antidepresivos triciclicos.

Se realizo un estudio observacional, sin establecer causalidad, pero debemos tenerlo en cuenta que en adultos mayores de 65 años la ingesta de alguna de estos medicamentos, en forma diaria, por mas de 3 años se observó una mayor incidencia de demencia.

"This large US prospective cohort study suggests a link between those taking high levels of anticholinergic medicines for more than three years and developing dementia in adults over 65.

The main statistically significant finding was in a group taking the equivalent of any of the following medications daily for more than three years: 

• xybutynin chloride, 5mg 
• chlorpheniramine maleate, 4mg 
• olanzapine, 2.5mg 
• meclizine hydrochloride, 25mg 
• doxepin hydrochloride, 10mg"

El articulo:

Gray SL, et al. Cumulative Use of Strong Anticholinergics and Incident Dementia. A Prospective Cohort Study. JAMA Internal Medicine. Published 26 January 2015

Este link explica muy bien y a fondo los puntos anconsiderar para evitar alarma y amarillismo:

http://www.nhs.uk/news/2015/01January/Pages/media-dementia-scare-about-common-drugs.aspx

Benjamin Hidalgo-Matlock

Skin Care Physicians of Costa Rica

4000-1054

2208-8206

Please excuse the shortness of this message, as it has been sent from a mobile device.

Incremento en la incidencia de Melanoma en Estados Unidos de NA.

Reportan duplucacion en la incidencia de melanoma en estados unidos en la poblacion general pero un incremento del 250% en la poblacion joven!

CDC: Incidence Of Melanoma Has Doubled In The US In The Last 30 Years.

The Los Angeles Times (6/3, Kaplan) "Science Now" blog reports that "the incidence of melanoma...has doubled in the U.S. in the last 30 years and is on track to remain high unless Americans take more precautions to protect themselves from ultraviolet radiation, the Centers for Disease Control and Prevention said" yesterday. The "Vital Signs study" was "published in the Morbidity and Mortality Weekly Report." The blog adds that while "Melanomas account for only 2% of skin cancers...they are the deadliest kind, according to the National Cancer Institute."

        On its website, CBS News (6/3, Cohen) reports that in a statement, Dr. Lisa Richardson, the director of the CDC's Division of Cancer Prevention and Control, said, "The rate of people getting melanoma continues to increase every year compared to the rates of most other cancers, which are declining." Dr. Richardson added, "If we take action now, we can prevent hundreds of thousands of new cases of skin cancers, including melanoma, and save billions of dollars in medical costs."

        Melanoma Rates Up Among US Children, Young Adults.HealthDay (6/3, Dallas) reports that research indicates that "melanoma...has increased by 250 percent among U.S. children and young adults since the 1970s." The findings were presented at the American Society of Clinical Oncology meeting.

Benjamin Hidalgo-Matlock

Skin Care Physicians of Costa Rica

4000-1054

2208-8206

Please excuse the shortness of this message, as it has been sent from a mobile device.