Examenes sin valoración...

Muchas veces, las personas se hacen exámenes de laboratorio sin una valoración previa, y muchas veces se ha demostrado que esto no es tan beneficioso como parece.

El presente estudio analizó el valor predictivo de los exámenes de alergia especifica a alimentos por detección en sangre de Ig E especifica a alimentos y encontraron que NO ayuda en determinar alergia alimentaria en pacientes con dermatitis atópica o si esta era relacionada a la misma.

DECEMBER 23, 2015

Food-antigen–specific immunoglobulin E (sIgE) levels did not help predict development of food allergy in a study involving more than 1,000 infants with atopic dermatitis at risk for such an allergy. 

Investigators tracked food allergy development during 2 phases of a trial evaluating pimecrolimus cream 1% in infants with mild-to-severe atopic dermatitis and no history of food allergy. They also measured sIgE for cow's milk, egg white, peanut, wheat, seafood mix, and soybean at baseline, as well as the end of each study period. 

Among the results:

• Nearly 16% developed at least 1 food allergy.

• 6.6% developed allergy to peanut, 4.3% to cow's milk, and 3.9% to egg white. 

• Levels of sIgE for milk, egg, and peanut increased with severity of atopic dermatitis.

Researchers assigned sIgE decision points for each food and tested predictive value. They found the value to be low for both established and newly developed decision points.

Citation: Spergel J,  Boguniewicz M,  Schneider L,  Hanifin J,  Paller A, Eichenfield L. Food allergy in infants with atopic dermatitis: Limitations of food-specific IgE measurements. Pediatrics. 2015;136(6):e1530-1538.