Association Found Between HS and Crohn’s Disease | Dermatology News

Association Found Between HS and Crohn's Disease

JAMA Dermatology; ePub 2018 May 23; Garg, et al

June 4, 2018

Patients with hidradenitis suppurativa (HS) are at risk for Crohn's disease (CD), according to a recent study. Therefore, gastrointestinal symptoms or signs suggestive of CD warrant additional evaluation by a gastroenterologist. Researchers conducted a cross-sectional analysis of data from patients with HS identified using electronic health records data, which included data from >50 million unique patients across all US census regions. They found:

• Of the 18,455,660 total population considered, 51,340 had HS (35,000 women).
• Of these patients with HS, 29,010 (56.5%) were aged 18 to 44 years; 17,580 (34.2%), 45 to 64 years; and 4,750 (9.3%), ≥65 years.
• Prevalence of CD among patients with HS was 2.0% (1,025/51,340), compared with 0.6% (113,360/18,404,260) among those without HS.
• Prevalence of CD was greatest among patients with HS who were white (2.3%), aged 45 to 64 years (2.4%), nonobese (2.8%), and tobacco smokers (2.3%).
• In univariable and multivariable analyses, patients with HS had 3.29 and 3.05 times the odds of having CD, respectively, compared with patients without HS.
• CD was associated with HS across all patient subgroups.

Citation:

Garg A, Hundal J, Strunk A. Overall and subgroup prevalence of Crohn disease among patients with hidradenitis suppurativa. A population-based analysis in the United States. [Published online ahead of print May 23, 2018]. JAMA Dermatology. doi:10.1001/jamadermatol.2018.0878.

Benjamin Hidalgo-Matlock

Skin Care Physicians of Costa Rica

4000-1054

2101-9574

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