Lipidos se pueden medir con o sin ayuno

More Evidence That Fasting Isn't Necessary Before Lipid Tests

By Amy Orciari Herman

Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM

A new analysis, published in JAMA Internal Medicine, adds to the evidence that nonfasting lipid measurements are as clinically useful as fasting measurements.

Nearly 8300 adults at increased cardiovascular (CV) risk had fasting and nonfasting lipid levels measured 4 weeks apart. Participants' total, LDL, and HDL cholesterol levels showed "negligible" differences between their fasting and nonfasting samples, while triglycerides were "modestly higher" in nonfasting samples.

During a median 3 years' follow-up, some 210 major coronary events occurred. Nonfasting and fasting lipid levels were similarly associated with incident coronary events — a finding that persisted in a subanalysis of patients without prior vascular disease. Additionally, nonfasting and fasting levels showed high agreement in terms of classifying patients into CV risk categories.

The researchers say their findings "provide robust evidence and more impetus for physicians to more broadly adopt nonfasting measurement of lipid levels for routine practice, in a manner consistent with ... recent guideline recommendations."

JAMA Internal Medicine article (Free abstract)

Background: NEJM Journal Watch General Medicine coverage of 2018 cholesterol management guideline (Your NEJM Journal Watch subscription required)

Background: NEJM Journal Watch General Medicine coverage of a 2016 review on nonfasting lipid levels (Free)

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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