Onicomicosis por fusarium

ORIGINAL ARTICLE

Fusarium onychomycoses in Switzerland—A mycological and histopathological study

Anna Rammlmair

Konrad Mühlethaler

Eckart Haneke

First published: 04 July 2019

https://doi.org/10.1111/myc.12964

The study demonstrates that Fusarium species are important nail pathogens also in Central Europe.

Summary

Onychomycoses in temperate climates are most commonly due to dermatophytes, particularly Trichophyton rubrum. Non‐dermatophyte nail infections are much less frequent, and their diagnosis requires a careful and repeated search for a potential dermatophyte that may have been overgrown in culture. A series of histological slides of suspected onychomycoses with uncommon fungal morphology prompted us to search for non‐dermatophytic moulds causing dermatophytosis‐like nail infections. Thirty cases were identified by culture as F solani, F oxysporum, F dimerum or F spp, and two more were only diagnosed histopathologically. None of these patients was immunocompromised. Treatment was mostly unsuccessful with terbinafine whereas itraconazole showed a moderately better treatment result; in all cases, a topical ciclopirox nail varnish in a hydroxychitosan base was added.