Otra causa de distrito inmunocomprometido

Journal Scan / Case Study · March 04, 2020

Varicella and Herpes Zoster Appearing Over Sites of Tinea Corporis

International Journal of Dermatology

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• The authors report 3 cases of herpes zoster or varicella infection over sites of healed superficial dermatophytosis as well as a single varicella infection within an active superficial dermatophyte infection under treatment.

• All 4 cases of superficial dermatophytosis had been treated with a combination topical steroid, antifungal, and antibacterial cream; however, the authors propose that this could not be the sole cause of overlying viral infection. They theorize that the sites of superficial dermatophyte infection had become immunocompromised districts within the skin, making the areas more vulnerable to subsequent viral infection.

– Caitlyn T. Reed, MD

The images in this article are amazing. The vesicles of chickenpox home in on areas of tinea corporis or recently treated tinea corporis with amazing alacrity, especially at the advancing margin of the tinea patches. This suggests that the innate immune system's "attack" on the dermatophyte is lessening immune surveillance toward "herpes zoster" virus carried throughout the body in the bloodstream, but affecting the skin only in these immunocompromised districts. Interested readers should read the article by Ruocco et al.1

Reference

1. Ruocco V, Ruocco E, Piccolo V, et al. The immunocompromised district in dermatology: a unifying pathogenic view of regional immune dysregulation. Clin Dermatol. 2014;32(5):569-576. https://www.sciencedirect.com/science/article/pii/S0738081X14000959

Abstract 

Herein we report the development and localization of herpes zoster or varicella over sites of healed superficial dermatophytosis (SD) in three patients (Figs. 1a,b and 2a) and varicella on sites of active SD under treatment in one patient (Fig. 2b,c).

International Journal of Dermatology

Varicella and Herpes Zoster Appearing Over Sites of Tinea Corporis, Hitherto Unreported Examples of Immunocompromised Districts: A Case Series

Int. J. Dermatol 2020 Feb 18;[EPub Ahead of Print], SB Verma, S Gupta, A Yadav, E Ruocco 

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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