Ocular Comorbidities in Patients With Hidradenitis Suppurativa

TAKE-HOME MESSAGE

• A total of 31,400 patients with hidradenitis suppurativa (HS) and 51,517,730 control patients were included in this study to compare ocular comorbidities in these populations. The authors found that 4360 (13.89%) of the HS patients had ocular comorbidities, whereas 1,654,320 (3.2%) of the control patients had ocular comorbidities (P < .001). A statistically significant odds ratio (OR) was noted for anterior uveitis in patients with HS (OR, 1.41; P < .001), along with episcleritis (OR, 2.06; P < .001), keratitis (OR, 1.54; P < .001), and conjunctivitis (OR, 1.27; P < .001). There was no statistically significant increased OR in HS patients for posterior uveitis, chronic uveitis, scleritis, or interstitial keratitis.

• This case–control study shows a higher burden of ocular comorbidities in the HS cohort compared with the control population. The authors suggest asking HS patients about ocular history and symptoms during office visits to determine whether an ophthalmology referral is warranted.

– Alex Noble, MD

Abstract 

Hidradenitis suppurativa (HS) is a chronic systemic inflammatory disorder of the terminal follicular epithelium in the apocrine gland–bearing skin. Clinically, it is characterized by lesions, including comedones, papules, pustules, nodules, and fistulas, that are mainly concentrated in axillae, perineal, and submammary areas.1

Other autoimmune diseases are associated with ocular comorbidities; however, there is a paucity of data on ocular comorbidities in HS.1-4 In this article, we aim to quantify the burden of ocular comorbidities in patients with HS.

JAMA Dermatology

Burden of Ocular Comorbidities in Patients With Hidradenitis Suppurativa

JAMA Dermatol 2021 Jan 06;[EPub Ahead of Print], RRZ Conic, G Fabbrocini, C Marasca, NL Bragazzi, W Abdulla, M Adawi, G Damiani 

Sent from my iPhone

Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

Please excuse the shortness of this message, as it has been sent from
a mobile device.