In a systematic review and meta-analysis published in Photodermatology, Photoimmunology & Photomedicine, the authors aimed to assess the effects of probiotics on skin photoaging. This study included 13 articles examining the effects of probiotics on skin photoaging in humans and mice. The administration of probiotics in mice reduced the matrix metalloproteinase levels and reversed the UV-induced increase in epidermal thickness, UV-induced trans-epidermal water loss, and UV-induced skin dehydration. The authors propose that oral probiotics seem to have anti-inflammatory and skin barrier-restoring properties, although they discuss the limitations of murine experiments and the lack of standardized concentration, dosing, and timing for the probiotic.

Photodermatology, Photoimmunology & Photomedicine

Volume 39, Issue 2 p. 122-131

ORIGINAL ARTICLE