Hoy hacemos una notificación en lo que son productos aplicados sobre la piel (tópicos) para el tratamiento del acné. Sabemos que cualquier cosa puede dar "alergia", inclusive existen las reacciones espontáneas, sin gatillo alguno, pero vale la pena recalcar donde se establece que cualquier producto puede dar reacción alérgica.
Adjunto el reportaje en Ingles, donde dice que varios productos que contienen peróxido de benzoilo y ácido salicílico pueden dar reacciones alérgicas y si hay síntomas de prurito ( picazón), dificultad respiratorio, cambio en el tono de la vos o hinchazón de lengua, al usar estos productos, deben suspender su uso inmediatamente, notificar a su dermatólogo o proveedor de salud y asistir a un servicio de urgencias.

FDA Warns About Serious Reactions to OTC Acne Products

By Amy Orciari Herman

Edited by Susan Sadoughi, MD, and Lorenzo Di Francesco, MD, FACP, FHM

The FDA is warning that "rare but serious and potentially life-threatening" allergic reactions may occur with some over-the-counter topical acne products containing benzoyl peroxide or salicylic acid. Symptoms — including dyspnea and swelling of the eyes, face, lips, or tongue — may appear within minutes to longer than a day after application.

The products in question include those marketed as Proactiv, Neutrogena, MaxClarity, Oxy, Ambi, Aveeno, Clean & Clear, and store brands.

From 1969 to 2013, roughly 130 serious reactions associated with such treatments have been reported to the FDA, most since 2012. It's unclear whether the reactions were caused by the active ingredients, the inactive ingredients, or both.

When recommending these products, the FDA says, providers should educate patients about the symptoms of serious reactions, including skin or mucosal changes, dyspnea, hypotension, or syncope indicative of anaphylaxis. They should advise patients to stop treatment if hives or itching occur, and to seek emergency care at signs of anaphylaxis.

FDA MedWatch safety alert (Free)

Background: NEJM Journal Watch Dermatology coverage of acne treatment recommendations (Your NEJM Journal Watch registration required)