Manejo Vitamina D en Norwich UK, en pacientes con Melanoma.

0. "At our centre, baseline vitamin D is measured at time of melanoma diagnosis. When levels are within normal range, dietary advice is given. If levels are <50nmol/L, vitamin D3 supplementation of 1200IU (30micrograms) is commenced once daily for at least 6 months. If severe deficiency is detected (<20nmol/L), then supplementation is increased. Calcium levels are monitored six weeks after to ensure no unmasking of hyperparathyroidism. Vitamin D levels are re-checked at 6 months. If levels have moved into normal range, supplementation of 400IU (10micrograms) is advised during the winter months. There remains debate to ideal levels of vitamin D. Our local range is 50-120nmol/L, though higher level (60-85nmol/L), depending on the season, has been suggested as at this level, parathyroid hormone reach a basal level and is not reduced with vitamin D supplementation (6,9)

   Our data suggests that measuring vitamin D levels may be of benefit in melanoma patients, with appropriate supplementation prescribed according to local/NICE guidance (8,10). In future, as vitamin D testing becomes more widely available and the correction of deficiency more commonplace, this service is likely to be undertaken in primary care. "

   
   

   Monitoring vitamin D in the melanoma patient – impact of sun avoidance on vitamin D levels of melanoma patients at a tertiary UK referral melanoma service
   M.C.I. Lo, J. Maraka, J. Garioch, W.G. John and M. Moncrieff
   Accepted manuscript online: 17 SEP 2016 09:46AM EST | DOI: 10.1111/bjd.15062