Cromomicosis tratamiento exitoso.
Successful treatment of chromoblastomycosis of 10-year duration due to Fonsecaea nubica
- This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/myc.12731
Abstract
We report a case of chromoblastomycosis due to presence of large plaque and verrucous hyperplasia lesions on the left upper limb, with elbow abnormal activities, in a 56-year-old male. The diagnosis of chromoblastomycosis was based on gross and microscopic morphologies, histopathological examination and clinical manifestation. Molecular tools were applied to identifying the causative agent: Fonsecaea nubica, which is rarely reported to be associated with chromoblastomycosis. The patient was initially treated orally with terbinafine (250 mg/day) and itraconazole (200 mg/day), subsequently patient received thermotherapy (45-50 °C, 3 hours/day) for one month. The patient was successfully cured. A literature review was performed to assess general features, treatment and outcome of chromoblastomycosis due to Fonsecaea nubica. All the five reviewed patients were male, over 30-years-old, and their lesions were occurred after traumatic inoculation.
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