Tratamiento ALopecia Frontal Fibrosante

FRONTAL FIBROSING ALOPECIA - TREATMENT WITH 5-ALPHA REDUCTASE INHIBITOR

This evidence-based update paper analyzed published studies on the safety and efficacy of 5-alpha reductase inhibitor in the treatment of frontal fibrosing alopecia (FFA).

Articles published between 2005 and 2017 were selected, analyzed, and classified according to the American College of Physicians outcome study grading system.

The results showed two studies with a moderate level of evidence that reported efficacy of 5-alpha reductase inhibitor in the treatment of FFA. There were reports of mild to moderate hair growth in four studies (one grade 2, one grade 3, and two grade 4). Evidence on safety aspects of the active ingredient was limited.

Despite the study limitations regarding methodology variation and detection of confounding factors, the authors concluded that patients with FFA treated with 5-alpha reductase inhibitors may achieve stability or reduction of disease progression in certain cases, but suggest a randomized, double-blind, controlled trial to be performed for more robust data.

J Eur Acad Dermatol Venereol. 2018 Mar 10. doi: 10.1111/jdv.14930. [Epub ahead of print]

5 alpha-reductase inhibitor treatment for frontal fibrosing alopecia: An evidence-based treatment update.

Murad A, Bergfeld W.

Benjamin Hidalgo-Matlock

Skin Care Physicians of Costa Rica

4000-1054

2101-9574

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