Tincion para Histoplasma

   Diagnostic tip: CD42b IHC stain for Histoplasma          

 

There are currently no antibodies specific for Histoplasma, which makes diagnosis challenging. While performing immunohistopathology on a biopsy of bone marrow infected with histoplasmosis, Ku and colleagues noticed that H. capsulatumexpresses a cell surface marker called CD42b (glycoprotein Ib), which is normally used to identify megakaryocytes and the platelets they produce. Further characterisation is needed to show whether this antibody is suitable for development into new diagnostics.

 

►  Find out more: Ku et al (2018) Use of CD42b immunohistochemical stain for the detection of Histoplasma

 

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 2224-0654
Momentum Escazu: 2101-9574

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