HPV Oral en mujeres

Oral HPV Fairly Common in Sexually Active Adolescent Girls

By Kelly Young

Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH

Oral human papillomavirus (HPV) is not uncommon among sexually active adolescent females, and the vaccine appears to be protective, suggests a JAMA Network Open study. 

Nearly 1300 sexually active females aged 13 to 21 in New York City had oral samples tested for HPV at baseline. Roughly 6% tested positive for oral HPV. Nearly 2% were positive for oncogenic types, while 0.2% had types included in the quadrivalent vaccine. Risk for oral HPV decreased with increasing time since their first sexual experience, "potentially reflecting the highlight transient nature of HPV infection," the authors write. 

Patients who received at least one dose of the vaccine had an 80% lower risk for oral HPV types included in the quadrivalent vaccine, relative to unvaccinated participants, although the authors note that few patients were unvaccinated. In addition, the presence of cervical HPV was associated with oral HPV.

The authors conclude: "This study's findings suggest that ... HPV vaccination is associated with a significant decrease in detection of HPV types in the oral cavity."

Commentators say the results are similar to what is observed in adult patients.

JAMA Network Open article (Free)

JAMA Network Open commentary (Free)

Background: NEJM Journal Watch Women's Health coverage of evidence of herd immunity against oral HPV (Your NEJM Journal Watch subscription required)

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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