Acne, Depresión y Ansiedad

Published in Dermatology

Journal Scan / Research · March 05, 2020

Acne Vulgaris and Risk of Depression and Anxiety

JAAD

TAKE-HOME MESSAGE

• In a systematic review and meta-analysis including 42 studies, depression and anxiety were more prevalent among those with acne than those without acne, with a mean correlation of r = 0.22 (P<.00001) for depression and r = 0.25 (P<.00001) for anxiety. When comparing adults versus adolescents, the magnitude of the associations was significantly stronger in adults.

• While the association of acne with depression and anxiety has been debated, this systematic review and meta-analysis quantified the associations and demonstrated a significant association of acne with depression and anxiety. Therefore, effective acne treatment is crucial, and clinicians may want to incorporate psychiatric screening or referral systems.

– InYoung Kim, MD, PhD

Abstract

BACKGROUND

Several studies have shown an association of acne vulgaris with depression and anxiety but a quantitative review has not yet been conducted.

OBJECTIVE

To conduct a systematic review and meta-analysis that elucidates the association of acne vulgaris with depression and anxiety.

METHOD

A systematic review and meta-analysis of literature published prior to October 1, 2019 from PubMed, PsycINFO, MEDLINE, and Cochrane databases was conducted. We used a meta-analytic approach to perform a random effects analysis comparing individuals with and without acne. Subgroup analyses between studies included age, study setting, and geographic region.

RESULTS

In all, 42 studies were included. We found a significant association of acne vulgaris with depression, r = 0.22 (95% CI: 0.17-0.26, p < .00001), and anxiety, r = 0.25 (95% CI: 0.19-0.31, p < .00001). Subgroup analyses and comparisons showed moderating influences based on factors including age, study setting, and geographic region.

LIMITATIONS

Inconsistency between publications regarding acne and outcome ascertainment, data reporting, and studies with no control group posed considerable barriers to synthesizing all available literature.

CONCLUSION

Because of increased risk for depression and anxiety, clinicians should pursue aggressive treatment of acne and consider psychiatric screening or referrals.

Journal of the American Academy of Dermatology

Acne Vulgaris and Risk of Depression and Anxiety: A Meta-Analytic Review

J Am Acad Dermatol 2020 Feb 20;[EPub Ahead of Print], DV Samuels, R Rosenthal, R Lin, S Chaudhari, MN Natsuaki 

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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