Queratosis Actinicas

Guideline highlights

• Although they often persist as chronic skin lesions, AKs can spontaneously involute, or most importantly, evolve into keratinocyte carcinoma if left untreated.

• Treatment options for AK include field-directed therapies, such as topical medications and photodynamic therapy, and lesion-directed therapies, like cryosurgery and laser ablation.

• Analysis of the evidence from a systematic review based on five research questions resulted in eighteen evidence-based recommendations and suggests there are several effective treatments available for AK.

• Strong recommendations were made for the use of UV protection, cryosurgery, topical imiquimod, and 5-FU. Conditional recommendations were made for the use of PDT and diclofenac for the treatment of AK, both individually and as part of combination therapy regimens.

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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