Dermatología en Costa Rica

Thursday, October 13, 2022

Cremas utiles en DA

Daily, Customized Skin Care Routine Treats Babies and Children With Atopic Dermatitis

Emollients containing licochalcone A, menthoxypropanediol, ceramides, and omega 3 and omega 6 fatty acids are highly effective for the treatment of atopic dermatitis (AD) in babies and children, according to results from a study presented at the 2022 Annual Meeting of the European Academy of Dermatology and Venerology (EADV) Congress, held from September 7 to 10, 2022 in Milano, Italy.

A total of 73 patients, aged 0 to 15 years, were included in the study since as many as 20% of children may have AD, researchers noted. A daily, customized skin care routine tailored to atopic skin needs is recommended to prevent flare-ups; however, skin barriers differ and vary greatly in children and adults.

Researchers conducted 2 prospective, uncontrolled trials that included newborns (0-4 weeks), babies (4-12 weeks), and children (≤15 years) with acute AD flare-ups. Experts and patients' parents assessed the efficacy of 2 products: acute care cream containing emollients with licochalcone A and menthoxypropanediol, and a basic cleansing formula containing licochalcone A, ceramides, and omega 3 and omega 6 fatty acids, respectively. They used SCORAD (0-18 points), Investigator Global Assessment (IGA; 5-point scale) and the Itch Visual Analogue Scale (VAS; 1-10) in their assessment.

In the initial 8-week study, acute care cream was applied twice daily for the first 2 weeks, with application of the basic cleansing formula during the remaining 6 weeks for maintenance. In the second, a 6-week study, a care cream containing emollients with licochalcone A, ceramides, and omega 3 and omega 6 fatty acids was applied at least once daily. A cleansing product with more than 60% natural oils was used once daily from weeks 4 to 6.

Acute skin care formulations conta[i]ning Emollients PLUS Licochalcone A and Menthoxypropanediol can significantly support atopic skin during a flare-up, while daily basic care with Emollient PLUS Licochalcone A, Ceramides, and Omega 3 [and omega] 6 fatty acids can create a stable skin condition.

In the first study, researchers found that patients' (n=41) flare-ups were significantly reduced throughout the course of treatment, and Itch VAS improved by almost 100% (5.1 to 0.048). No adverse events were seen. Similar results were recorded for patients (n=32) in the second study as 100% of experts and patients confirmed high tolerability of both products, 100% of parents confirmed the cleanser was gentle and efficient for cleaning their baby's skin, and 97% confirmed the care cream treated babies' dry skin well.

Researchers concluded, "Acute skin care formulations conta[i]ning Emollients PLUS Licochalcone A and Menthoxypropanediol can significantly support atopic skin during a flare-up, while daily basic care with Emollient PLUS Licochalcone A, Ceramides, and Omega 3 [and omega] 6 fatty acids can create a stable skin condition." They continued, "Further studies are needed to assess the impact of a regular and early skin care in newborns and babies on sleep quality, overall patients' quality of life and long term prognosis of AD."

Presented at: the 2022 European Academy of Dermatology and Venerology (EADV) Congress Annual Meeting: September 7-10, 2022. Abstract/Poster 1578.


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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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