Prenatal Maternal Risk Factors Contributing to Atopic Dermatitis: A Systematic Review and Meta-Analysis of Cohort Studies

The researchers found that gestational diabetes, maternal history of allergy, and prenatal history of eczema (odds ratios, 7.2, 2.14, and 2.46, respectively) were major determining nonmodifiable risk factors in early manifestation of AD in children. Leading causes of early AD manifestation also included maternal exposure to industrial products, exposure to antibiotics during pregnancy, and passive smoking during pregnancy (odds ratios, 1.89, 3.59, and 2.60, respectively).

"Both genetic and environmental factors play a pivotal role in early manifestation of AD," the authors write. "Further studies are required [to] clarify the mechanisms and ways to manage the modifiable factors to the least."

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Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica

Clinica Victoria en San Pedro: 4000-1054
Momentum Escazu: 2101-9574

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