Incremento de enfermedades cardio y cerebrovasculares en pacientes con enfermedades dermatológicas inflamatorias.

Inflammatory Skin Disease & CVD/Cerebrovascular Risk

Am J Clin Dermatol; ePub 2017 May 22; Kwa, et al

May 31, 2017

Psoriasis, pemphigus, bullous pemphigoid (BP), atopic dermatitis or eczema (AD-E), and hidradenitis were all associated with increased cardiovascular and cerebrovascular risk, especially at younger age, according to a recent study. Researchers analyzed data from the 2002–2012 National Inpatient Sample, including a representative 20% sample of all US hospitalizations (n=72,108,077 adults). They found:

• In multivariate logistic regression models with propensity score matching, patients hospitalized with vs without a diagnosis of the inflammatory skin diseases examined had higher odds of obesity for pemphigus, BP, AD-E, psoriasis, and hidradenitis.
• Inflammatory skin disease was also associated with significantly higher odds of different cardiovascular risk factors, including hypertension and diabetes mellitus with complications, as well as vascular, cardiovascular, and cerebrovascular disease, including peripheral vascular disease, peripheral and visceral atherosclerosis, pulmonary circulation disorders, congestive heart failure, history of transient ischemic attack, and cerebrovascular disease.
• In stratified analyses, multiple inflammatory skin diseases were associated with significantly higher rates of obesity, hypertension, and/or diabetes in patients aged <50 years and females.

Citation:

Kwa MC, Silverberg JI. Association between inflammatory skin disease and cardiovascular and cerebrovascular co-morbidities in US adults: Analysis of Nationwide Inpatient Sample Data. [Published online ahead of print May 22, 2017]. Am J Clin Dermatol. doi:10.1007/s40257-017-0293-x.