Medicamentos orales para rosacea ocular... hay que volver a traer la eritromicina!

SYSTEMIC THERAPY FOR OCULAR AND CUTANEOUS ROSACEA IN CHILDREN

This retrospective study aimed to analyze children with rosacea presenting ocular symptoms, submitted to systemic treatment, particularly addressing remission and relapse rates.

Medical records of 19 children with ocular rosacea treated with a systemic antibiotic were reviewed. Of these, nine were selected for further analysis.

The results indicated that 89.5% of the children had blepharitis, 78.9% had conjunctivitis, 63.2% had a hordeolus, and 9 female patients (47.4%) had corneal involvement.

Erythromycin (n = 9) or roxithromycin (n = 1) were used in patients <8 years of age and doxycycline (n = 8) or minocycline (n = 1) in patients over 8 years of age.

The results indicated complete remission of ocular and cutaneous symptoms in 77.78% of patients who used erythromycin, 12.5% of the patients treated with doxycycline, and in the patient treated with minocycline. Partial remission occurred in 22.22% of patients treated with erythromycin, 87.5% of patients treated with doxycycline, and among the patient treated with roxithromycin. Recurrences occurred in 25% of patients treated with doxycycline (ocular and cutaneous), in patients treated with minocycline (cutaneous), and in 11.11% of patients treated with erythromycin (cutaneous).

The authors concluded that anti-inflammatory treatment of at least 6 months is necessary for complete remission of cutaneous and ocular rosacea.

J Eur Acad Dermatol Venereol. 2017 Jun 16. doi: 10.1111/jdv.14402. [Epub ahead of print]
Systemic therapy of ocular and cutaneous rosacea in children.
Gonser LI, Gonser CE, Deuter C, Heister M, Zierhut M, Schaller M.