Esclerodermia de inicio tardío es de peor pronóstico
Adults Who Develop SSc At An Older Age May Be At Greater Risk For Rapid Disease Progression Than Those With A Younger Age At Onset, Research Suggests
Medwire News (5/15, Kitt) reported, "Adults who develop systemic sclerosis (SSc) at an older age are at greater risk for rapid disease progression than those with a younger age at onset," investigators concluded in a study that "used data from 3281 SSc patients (79.7% female) who were enrolled in the registry of the German Network for Systemic Scleroderma, of whom 54.2% had limited cutaneous (lc)SSc, 34.8% had diffuse cutaneous (dc)SSc, and the remaining 11.0% had overlap SSc." After grouping patients "according to age at SSc onset...researchers found that there was a shift in the distribution of SSc subsets with age." For example, "over 10 years of follow-up, prognosis was worse for patients older than 60 years at disease onset, as shown by a significantly higher and earlier incidence of organ manifestations compared with the early-onset group of patients." The findings were published online in the journal Rheumatology.
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