Dermatología en Costa Rica

Thursday, May 07, 2015

Cremas con Urea previenen la frecuencia de recaídas en Dermatitis Atópica.

Un estudio publicado en la Revista Científica Acta Dermato-Venerológica,
Realizaron un estudio a doble ciego aleatorizado usando cremas con urea ( sustancia reparadora de la barrera epidérmica e inductora de los factores humectantes naturales), donde observaron que el utilizar estas crema induce períodos de remisión y estabilidad más prolongados.

  • In this double-blind clinical trial, patients with atopic dermatitis (AD) who were randomized to use a urea-containing moisturizer had a 37% reduced risk for AD relapse relative to patients randomized to a reference cream containing no barrier-strengthening ingredients. Users of the urea-containing cream also had a significantly reduced median time to relapse when compared with those who used the reference cream (22 vs 15 days). Both creams were safe and well-tolerated.
  • The use of a barrier-improving cream (5% urea) in AD patients significantly reduced the risk of AD relapse and may be a superior option for maintenance therapy than creams without barrier-strengthening qualities.

Acta Dermato-Venereologica
Comparison of Moisturizing Creams for the Prevention of Atopic Dermatitis Relapse: A Randomized Double-Blind Controlled Multicentre Clinical Trial
Acta Derm Venereol 2015 Apr 28;95(5)587-592, U Åkerström, S Reitamo, T Langeland, M Berg, L Rustad, L Korhonen, M Lodén, K Wirén, M Grände, P Skare, Å Svensson 

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