Dermatología en Costa Rica

Sunday, March 05, 2017

Doxiciclina util en penfigoide ampolloso

CONFERENCE COVERAGE 

For bullous pemphigoid, doxycycline noninferior to prednisolone, but safer

Key clinical point: While not as effective as prednisolone, doxycycline was significantly safer for elderly patients with bullous pemphigoid.

Major finding: At 6 weeks, treatment succeeded in 74% of the doxycycline group and 91% of the prednisolone group; severe adverse events occurred in 18% and 36%, respectively.

Data source: The BLISTER trial randomized 253 patients.

Disclosures: The trial was run in collaboration with the Nottingham Clinical Trials Unit, the UK Dermatology Clinical Trials Network, and the Medical Research Council Clinical Trials Unit. Dr. Harman had no financial disclosures.

Benjamin Hidalgo-Matlock
Skin Care Physicians of Costa Rica
4000-1054
2208-8206
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