Pacientes con Dermatitis Atópica presentan mayor riesgo de infecciones sistémicas.

Published in Dermatology

Journal Scan / Research · March 27, 2017

Increased Risk of Cutaneous and Systemic Infections in Atopic Dermatitis

Journal of Investigative Dermatology

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• This large cohort study using The Health Improvement Network, which is representative of the general UK population, revealed that multiple cutaneous and noncutaneous infections are more common in people with atopic dermatitis (AD) compared with those without. In particular, people with AD had a 55% increased odds of impetigo, 27% increased odds of streptococcal throat infections, a threefold increased odds of molluscum contagiosum, and a twofold increased odds of otitis media.

• Individuals with AD are likely to be at increased risk for both cutaneous and noncutaneous infections, highlighting the need for infectious screening and prevention programs aimed at this patient population.

  – Jeffrey Scott, MD

Atopic dermatitis (AD, also known as atopic eczema or eczema), is characterized by skin barrier and immunologic dysfunction. Viral and bacterial super-infection of cutaneous lesions including eczema herpeticum and staphylococcus aureus in patients with severe disease is well documented (Ong and Leung, 2016, Weidinger and Novak, 2016). Whether the general population of patients with AD has an increased risk of these and other types of infections due to an impaired skin barrier and/or immunologic dysfunction is unclear.

Increased Risk of Cutaneous and Systemic Infections in Atopic Dermatitis—A Cohort Study

J Invest Dermatol 2017 Feb 12;[EPub Ahead of Print], SM Langan, K Abuabara, SE Henrickson, O Hoffstad, DJ Margolis